Top 10 Pharma Drug Discovery and Delivery Capital Raises in the U.S. – April 16th to 31st, 2025
Several interesting transactions closed in the Pharma Drug Discovery and Delivery sector over the past two weeks. If you would like more info on these deals or would like to discuss the capital raising market for your company, please contact me.
PIPE
- Jade Biosciences, focused on developing therapies to address critical unmet needs in autoimmune diseases, received $300 million of development capital from Driehaus Capital Management, Frazier Healthcare Partners, Great Point Partners, Soleus Capital, OrbiMed, Samsara BioCapital, Deerfield Management, Versant Ventures, RA Capital Management, Venrock, Deep Track Capital, Franklin Templeton, RTW Investments, Braidwell, Logos Capital, Avidity Partners, Blackstone and Fairmount Partners on April 28, 2025, through a private placement.
- Rezolute, a biopharmaceutical company that develops novel, sustained-release injectable therapies, received $81.06 million of development capital from Blackstone, Great Point Partners, Marshall Wace, Woodline Partners, Nantahala Capital Management, Federated Hermes and Squadron Capital Management on April 25, 2025, through a private placement.
Merger/Acquisition
- Aerovate Therapeutics, a clinical-stage biopharmaceutical company focused on developing drugs that improve the lives of patients with rare cardiopulmonary disease, was acquired by Jade Biosciences through a reverse merger, resulting in the combined entity trading on the Nasdaq Stock Exchange under the ticker symbol JBIO on April 28, 2025.
- Chimerix, a biopharmaceutical company based in the United States that engages in the research, development, and commercialization of medicines was acquired by Jazz Pharmaceuticals for $935 million on April 21, 2025.
Later Stage VC
- Glycomine, developer of orphan drugs designed to treat rare disorders of metabolism and protein misfolding, raised $115 million of Series C venture funding in a deal led by Advent Life Sciences and CTI Life Sciences Fund on April 16, 2025.
- Apnimed, developer of a pharmacologic therapy designed to target, with simple orally dosed medicines, the key underlying neurobiological mechanisms that lead to airway obstruction, raised $16.5 million of Series D venture funding from investors on April 24, 2025, putting the company’s pre-money valuation at $390 million.
Early Stage VC
- LTZ Therapeutics, developer of novel immunotherapies designed to treat patients suffering from cancer and other diseases, raised $40 million of Series A+ venture funding in a deal led by Wanwu Growth Venture Capital and Zoo Capital on April 24, 2025.
- Nova Anchora, operator of a biotechnology company intended to develop advanced protein therapy, raised venture funding from DEBRA Research, Epidermolysis Bullosa Medical Research Foundation and EB Research Partnership on April 29, 2025.
Seed Round
- Acelot, operator of a biopharmaceutical company intended for drug discovery, raised $6.5 million of Series A seed funding from investors on April 24, 2025, putting the company’s pre-money valuation at $39.5 million.
- Florey Biosciences, developer of engineered probiotics designed to support and improve the human microbiome, raised $1.4 million through the combination of Seed-1, Seed-2, and Seed-3 funding from investors on April 28, 2025, putting the company’s pre-money valuation at $4 million.
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Sources: Information on this page was derived from a variety of sources including Bloomberg, Company Websites, Crunchbase, PitchBook and other news outlets. Castle Placement™ does not warrant or guarantee this information, nor makes any representations as to the accuracy of the information. For more Risks, see CPGO Risks and Disclaimers.











